At Syncore Labs, we have designed and synthesized over 300 novel and drug-like scaffolds.  We can also design and synthesize novel scaffolds tailored to your need. Please feel free to contact us for your drug discovery needs.

Scaffolds are usually rigid, hetero-cycle based structures with functional groups that can be further modified. A large number of marketed drugs contain core scaffolds, for example, Atorvastatin, Sildenafil, and Erlotinib, to name a few. It appears that the major role of the scaffold in a drug molecule is to position those attached functional groups in a right direction and facilitate their proper interaction with biological targets. Therefore, tuning scaffolds is a proven strategy to discover drugs with improved therapeutic index.